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Showing posts with label lupron. Show all posts
Showing posts with label lupron. Show all posts

14 July 2010

Lupron Left, Lupron Right

I started my shots of Lupron 8 days ago, and yes, I am cranky. I also have a headache. This is the third time I have been on this particular drug. The first time was during my second IVF cycle last fall. The second was just a month ago. That cycle was postponed, so I took an extra 11 day of Lupron for no reason. Good times.
Every night, I give myself the shot after icing my belly, and I record the event in my calendar. Sources say that you should alternate the side of the belly you inject every day. This isn't a huge deal with Lupron, because the site itself isn't very bothered by the liquid, but it becomes more important when you add in the other shots later in the cycle because they cause redness and irritation and large welts that span the valley of the oblique muscles. All I can say is, I don't know how anyone does this without an ice-pack.
For now, it's just a running line on the bottom of my day planner: Lupron Left, Lupron Right, Lupron L, Lupron R. And I wait for AF, so I can add more needles to my repertoire.

25 October 2009

Long Long Lupron

And now a bit of the practical. I have started the Long Lupron IVF protocol.

For most people, this protocol begins with going on birth control pills, and I had already started to take them after a surgery I had to remove uterine fibroids in August. (The fancy name is a laparoscopic myomectomy.)

I have recently moved to a small town in Oregon, and there is only one fertility doctor in town. He uses the birth control pill and and an injectable called Lupron to get everyone in the current protocol on the same calendar. This allows him to organize his time so he can do all the egg retrievals and embryos transfers in the same week, which apparently leads to better results.

If you don't count the time on birth control, I am on day three of my protocol. If you want to know the nitty gritty of the process, here's my current nightly fertility regimen:
  1. The birth control pill
  2. A prenatal vitamin
  3. A baby aspirin (the purpose of which is, I think, to increase blood flow to my ovaries.)
  4. 10 units of Lupron in shot form (with a needle, not a glass.)
The idea is that this use of Lupron puts you into chemical menopause for two weeks before you start the other shots, the ones that stimulate the growth of the follicles that produce the eggs. Erin, are these the right verbs to use?



Chemical Menopause: "Egads," you exclaim. "The whole point of this is to beat menopause! To outsmart my infernal biological clock!" You might be agitated, and cranky, and you have not even started the Lupron yet. Well, I will share that so far, chemical menopause has not been as terrible as I feared. I don't know about you, but I mostly associate menopause with hot flashes. What I have had is more akin to the feeling you might get from a warm brandy. This is not a problem right now, as I am adjusting to a cooler, rainier climate here in Oregon and have not had alcohol since the day my father died. (One token glass of white wine with my mother at a restaurant, when she couldn't bear to head home to an empty house.) But the warm brandy flush might be alarming if you were not expecting it, or if you were giving yourself Lupron shots in Texas in August. The only other symptom I have so far, which has little to do with the weather, is a headache. Not a migraine, not a sinus headache, nothing too out of the ordinary. Just another hormonal headaches like all of the other hormonal headaches I have had in life. Irritating and persistent, but manageable. I have not had the crazy mood swings or nausea, or any of the highly unpleasant symptoms other women have reported on other blogs. But there is still time!

After all, it must be called the long Lupron protocol for some reason other than the charms of alliteration...

Will Someone Die Every Time I do IVF?

As you may recall, my father was diagnosed with stage 4 pancreatic cancer just after I went through my embryo transfer for IVF. And, as I started this process again, and tried to articulate the particular strands of trepidation I was feeling, the thing I was not telling people was that I was wondering whether someone would die every time I did IVF. To be clear, even though I am an only child, I don't really believe that everything in the world revolves around me. But I know about the circle of life, both from the Lion King and from that movie where death takes a holiday, and I know that usually, someone, somewhere is leaving this mortal plane when someone else is arriving via birth. Really, God, I get it. It does not have to be illustrated for me with such a direct connection as it was in the spring.

But apparently God, or the Powers that Be, or the Great Narrative Arc of my life feels otherwise.

Because I started my Lupron shots on Friday night, and today I have learned that another loved one is dying of cancer in the very near future.

Last Thanksgiving, while my parents were visiting us in California, we found out that a close friend of theirs, Virginia, was diagnosed with lymphoma. She had started treatment, but, with a variety of pre-existing conditions (including congestive heart failure), no one thought she had long to live. When I started IVF and my father was diagnosed, my mother and I were really not able to call or help or even really think about Virginia's condition. Luckily, she has a nephew who really stepped in. While my father was on life support and in his final days, the nephew moved Virginia to an assisted living facility near his house.

Now, Virginia has not had an easy life. Her first husband was a fighter pilot, and was MIA in Vietnam. She remarried a squadron-mate of his, and they had a son. When their son was 8, he was killed by a drunk driver on the sidewalk in front of their house. We met them a few years after this, and Virginia and her husband Bob took an instant liking to me. They took trips with us, to Hawaii, and the Caribbean and France. They wrote cards and called and spent holiday after holiday with us. And then, in 1991, when I was caught up in the whirlwind of college, Bob died of cancer. Virginia was alone. She did not have any siblings. She had lost both of her parents. Really, her nephew was her only relative. And we were the next closest thing.

A week after my father's funeral, I drove my mother down to see her. We had a terrible dinner in her assisted living facility, but she was happy to see us. She complained about her room; she complained about the food; she complained about how old and boring and lifeless her new house-mates were. Honestly, she didn't even seem sick anymore. She sent us out to buy some bottle of wine and some Doritos. And then my mother and I drove back up to my mother's house to continue the strangely sad and technical work of executing my father's estate, writing a new will for my mother, and preparing for the other major life transitions I was about to go through (including a surgery and a move to a different state.)

And now, just as I've started the long Lupron protocol for IVF, Virginia has moved to a hospice. There is a tumor in her spine and possibly one in her brain. She told her nephew that she is not afraid of dying, she is only afraid of dying alone. And he has promised her that he will be there for her.

And I will continue my protocol. I will not make plans to fly across country to see her, because, as my Reproductive Endocrinologist reminded me, I am not as young as I was six months ago.

And if Virginia does die alone, I will always feel I have failed her.